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Check for drug interactions

Adverse Drug Reactions are the 4th leading cause of death in the U.S.

GeneMedRx drug interaction software can help reduce the risk.

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Diabetes


Are you taking or considering oral hypoglycemic medication to treat or prevent diabetes?

Have you experienced side effects?

Has the medication not had the desired effect?

If you answered yes to any of these questions, you are not alone. Millions of Americans currently take cardiovascular medications to treat or prevent heart disease and many have had problems finding the right drug and dose. This is not surprising to people that study genetics - research shows that of all the clinical factors such as age, sex, weight, general health and liver function that alter a patient's response to drugs, genetic factors are the most important.

Over half of all medications including the majority of oral hypoglycemic medications for diabetes are metabolized by two enzymes in the liver called CYP2C9 and CYP2C19. Your genes are the main factor determining the level of these enzymes in your liver- if you have too much of the enzyme, you process the medication too quickly, too little of the enzyme and the medication builds up in your bloodstream potentially causing adverse reactions or side effects. Without knowing your genetics, your physician may need to go through months of trial-and-error prescribing to find the right drug and dose for you.

Population Frequency of Cytochrome P450 (CYP) Metabolizer Types

  Poor
(no or low enzyme levels)
Intermediate (reduced enzyme levels) Extensive (normal enzyme levels)

CYP2C9

4% 38% 58%
CYP2C19 3-21%

24-36%

79-97%

Affected Diabetic Medications

glimepiride
glipizide
glyburide
tolbutamide

Now you can help your healthcare provider optimize your response to diabetic drugs and many other medications by ordering DNA testing. Your results will be entered into our personalized medication management software, GeneMedRx You or your healthcare providers can log in to see if current or future medications are predicted to cause drug-drug or drug-gene interactions so dosage and selection can be catered to your needs. You receive a 90-day subscription free with your testing; additional one year extensions are available for a nominal fee. Of course, your DNA never changes so the testing only needs to be done once in a lifetime.

Click here to view a list of drugs for which DNA testing will be helpful.

The Testing Process

The process is simple. You can order testing directly if you have a physician prescription or your healthcare provider can request testing for you. We send a cheek swab collection kit with directions by mail. Use the return mailer to submit samples and receive results in ten days or less. Faster testing is available for an additional charge. Call a DNA testing consultant at (800) 523-3080 for details and to order.

Note: Testing is currently not available to New York residents and requires a prescription from a physician.

Questions? Call us at 1-800-523-3080
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Pharmacogenetic testing can help guide clinical medication management
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What our clients say...

"I just wanted to call and tell you that my physician switched my medications based on my test results, and I cannot describe how much better I feel. You have made a believer out of me, my family, and my physician. I hope this testing becomes routine before anyone is placed on long term medication."
- PY, Eirie, CO